Anti hypertensive drugs Pharmacology | Medi tutorial

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by, Fojla Rahman Zia
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Antihypertensive drugs

Hypertension is defined as a sustained diastolic bp 90 mmHg or greater accompanied by an elevated systolic bp 140 mmHg or greater in  subjects who are not taking antihypertensive medication.

Antihypertensive drugs includes :
A. Diuretics
B. Sympatholytic drugs
C. Vasodialators
D. Calcium channel blockers
E. ACE inhibitors
F. Angiotensin Receptor blocker.

A. Diuretics:
( thiazide and related drugs)
Hydrochlorothizide
Chlorthalidone.

(loop diuretics)
Frusemide
Bumetanides
Torsemide
Ethacrynic acid.

(k+ spareing diuretics)
Amilonide
Spironolactone.

B. Sympatholytic drugs:
(centrally acting drugs) 
Methyl dopa, Clonidine.

(adrenergic neuron blocking agents)
Guanethidine, Reserprine.

(B adrenergic antagonist)
Propranolol , Timolol
Atenolol, Metaprolol, Acebutolol.

(alpha-- adrenergic antagonist)
Prazocin, Terazocin, Doxazosin,
Phenoxybenzamine, Phentolamine.

C. Vasodialators:
(arterial) 
Hydralazine
Diazoxide

(both arterial and venous)
Sodium nitropruside

D. Calcium channel blockers:
(Dihydropyridines)
Nifedipine
Nicardipine
Amlodipine

(Non dihydropyridines)
Diltiazem
Verapamine.

E. ACE inhibitors:
Captopril
Enalapril
Lisinopril
Ramipril.

F. Angiotensin Receptor blocker:
Losartan 
Valsartan
Candesartan
Olmesartan

Telmisartan.
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